[NMusers] Vertex Pharmaceutical - Sr. Pharmacometrician/Associate Director Position (US & UK)

Sr. Pharmacometrician/Associate Director, 1040-01B >Send this job
description to a
friend!<http://www.vrtx.com/jobs_email.php3?tid=1&job_id=1389> This
individual will be responsible for assisting with Vertex Clinical
Pharmacology studies and may serve as the key person in the Clinical
Pharmacology department for one of the company's program. Specifically,
he/she will analyze PK/PD data from clinical studies (Phase I-IV), using
NONMEM, WinNonlin, SPLUS or SAS, and will write reports for regulatory
submissions; provide scientific input for Clinical Protocols, clinical
development plans, Investigator Brochures, and the Clinical Pharmacology
section of INDs and NDAs; and interact with contract research organizations
(CROs). Also, he/she will be expected to independently develop clinical
pharmacology analysis plans, evaluate clinical trial data using advanced
exploratory data analyses techniques, and perform clinical trial simulations
and apply novel pharmacometric principles to assigned studies. Supervision
of department staff may be required.

Requires a PhD in Pharmaceutics, Clinical Pharmacology, Biostatistics,
Chemical Engineering or Mathematical Biology, plus 4-7 years in the
pharmaceutical industry or within a regulatory agency. Candidates with more
experience will be considered for the Associate Director position. All
candidates must have substantial knowledge of the requirements for the
design, conduct, analysis, and report writing for regulatory submissions,
in-depth understanding of drug metabolism and PK/PD principles, experience
working with SPLUS or SAS and NONMEM, and an understanding of clinical trial
simulation and integration of PK/PD modeling in drug development. Must have
good verbal and written communication skills.

Apply on-line at www.VRTX.com


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Received on Thu Dec 07 2006 - 16:21:58 EST