RE: [NMusers] Minimum patients number...

There is no straight answer to your question. It depend heavily on the
model, on the noise in the data, on the interindividual variability, on
the time points at which the observations are recorded, etc..
Serge Guzy
President POP-PHARM


-----Original Message-----
From: owner-nmusers_at_globomaxnm.com [mailto:owner-nmusers_at_globomaxnm.com]
On Behalf Of Ahmed Hawwa
Sent: Thursday, January 25, 2007 3:22 PM
To: nmusers_at_globomaxnm.com
Subject: [NMusers] Minimum patients number...

Dear All,

Any idea about the minimum number of patients needed to produce
significant results using NONMEM. What about the number of samples from
each patient?

Our experience indicates that a minimum of 40 patients with 4 samples
from each patient is required to produce good results.

Ay idea is too much appreciated..

Yours,
Ahawwa


 
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Received on Thu Jan 25 2007 - 19:43:36 EST