RE: [NMusers] COX Proportional Hazard Model with Time Dependent Covariate

From: Nanayakkara, Nuwan <Nuwan.Nanayakkara_at_amylin.com>
Date: Tue, 3 Jul 2007 10:53:43 -0700

For (2), take a look at Survival Analysis Using SAS: A Practical Guide:
Books: Paul D. Allison by Paul D. Allison.


________________________________

From: owner-nmusers_at_globomaxnm.com [mailto:owner-nmusers_at_globomaxnm.com]
On Behalf Of Zhao, Liang
Sent: Monday, July 02, 2007 2:34 PM
To: nmusers_at_globomaxnm.com
Subject: [NMusers] COX Proportional Hazard Model with Time Dependent
Covariate


Dear All,
 
I have the following questions regarding with COX survial model with
Time Dependent Covariate that needs your experience and expertise
 
(1) Even we can do it with S-Plus or SAS, it can not be handled by
NONMEM, am I right? If I am wrong, who has started the work?

(2) How to make predictions with time-variant covariates based on COX
model using S-plus or SAS, if not NONMEM?
 
The question is asked because certain epidemic diseases are
season-sensitive and none assumption on base hazard is advantageous over
parametric approaches. Thank you in advance!
 
Liang Zhao

Received on Tue Jul 03 2007 - 13:53:43 EDT

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