[NMusers] autoinhibition

Dear nmusers,

Could anyone support me with nonmem code for a drug
undergoes in vivo hepatic metabolism leading to formation
of a metabolite. This metabolite has the ability to
inactivate parent drug transformation. Both parent and
metabolite data can be fitted with a single model of
two-compartment.

thanks in advance

khaled
Received on Fri Jun 22 2007 - 06:50:05 EDT