Re: [NMusers] Does NONMEM deal with more than one DV?

I would suggest letting the two forms be represented by two "compartment" with interconversion rate constants.? In other words, treat this as you would if you had parent and metabolite.

-----Original Message-----
From: Shen, Jun <Jun.Shen_at_stjude.org>
To: nmusers_at_globomaxnm.com
Sent: Mon, 28 Jan 2008 4:13 pm
Subject: [NMusers] Does NONMEM deal with more than one DV?





Hi, everyone,

?

If a drug has two forms (dosed with one form and converted to the other over time) and I have the data for the two forms, can NONMEM model that altogether? And how? Appreicate any comment. Thanks.

?

Jun



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Received on Mon Jan 28 2008 - 16:21:03 EST