From: Ramalingam Sankaran sankaram@Stanford.Edu
Subject: [NMusers] FWORK ERROR  
Date: Thu, March 11, 2004 2:01 pm  

Hi All!
  Will somebody please comment on the following error message:
"an error was found in the control statements. The characters in error are 
: FWORK
36 error has occured while creating the required files"
The very same control file worked just fine when I had only one individual 
but NONMEM figured this error when the number of individuals went up to 12.
Does it have something to do with the number of individuals? I think not 
,because my data are from merely 12 patients with their plasma drug 
concentrations ,doses  EVID, and MDVs.
Interestingly, only one another NONMEM user has sent in a similar help-call 
in the Users forum way back in 2001, but unfortunately I could not find any 
replies for that.
I hope someone replies this time and guys like me would stand clarified on 
this issue.
Thanks
Ram

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From: Bachman, William (MYD) bachmanw@iconus.com
Subject: RE:[NMusers] FWORK ERROR  
Date: Thu, March 11, 2004 2:36 pm  

In my experience, that error message has been associated with an improper
NONMEM installation or a compiler bug.  If you can run the control5 test
program "nmfe5 control5 report5.txt" without this error, you can be assured
that NONMEM is installed correctly and that the error is not due to having
12 individuals in the data set.

nmconsult@globomaxnm.com
GloboMax®
The Strategic Pharmaceutical Development Division of ICON plc
7250 Parkway Drive, Suite 430
Hanover, MD 21076 
Voice: (410) 782-2205
FAX: (410) 712-0737

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From: Ramalingam Sankaran sankaram@Stanford.Edu
Subject: RE:[NMusers] FWORK ERROR  
Date: Sun, March 14, 2004 4:09 pm  

Hi !
Thanks very much for the only response that I had.
As was sugessted,I tried running control5 and it was successful. So, going by what was said,
it is neither improper installation nor an issue of number being 12 individuals.
Sadly, there is no mention of this error in the on-line help or in the printed
manuals, at least as far as I can search and see.
Here is the recalcitrant and mysterious error once again
""an error was found in the control statements. The characters
in error are 
: FWORK
36 error has occured while creating the required files"
For those who are reading this message for the first time, let me restate that the the
control stream worked just fine when I pulled out 11 patients out of the data-set but
the moment all the 12 patients were in , this error message flashed. In fact, when I
added just one more individual and took it up to two, this error message came on.
I await some guidance from the group.
Thanks
Ram 

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From: billbachman billbachman@comcast.net
Subject: RE:[NMusers] FWORK ERROR  
Date:Sun, March 14, 2004 4:41 pm  

The information that you have provided is just not sufficient to diagnose the problem. 
If the information is not proprietary, you may want to supply the control stream
and the two person data file to allow someone to reproduce the issue.

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From:Nick Holford n.holford@auckland.ac.nz
Subject: RE:[NMusers] FWORK ERROR  
Date: Sun, March 14, 2004 6:06 pm  

Is it possible you are running out of disk space for your work files? The error
message you provide suggests an operating system problem rather than a problem with
NONMEM.
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Nick Holford, Dept Pharmacology & Clinical Pharmacology
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email:n.holford@auckland.ac.nz tel:+64(9)373-7599x86730 fax:373-7556
http://www.health.auckland.ac.nz/pharmacology/staff/nholford/
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