From: Örjan Nordle 
Subject: [NMusers] Problems with Digital Visual Fortran vers 5.0 on Windows NT 4.0
Date: Tue, 19 Mar 2002 21:13:00 +0100

Dear NONMEM users,
I have some problems with my installation of NONMEM on my new 933 MHz Intel
processor running Windows NT 4.0 (Digital Visual Fortran vers 5.0).
Some problems stop when the same problem runs on an older 90 MHz Intel
processor running Windows 95. The software is not as good as the old one. I
know that there was a patch but I can not locate it on the web. Will this
patch solve my problem? Will the latest version of Compaq Visual Fortran
solve my problem?

I have tried op=/optimize:4 /fltconsistency /fpe:0 as well as no
optimization without solving the problem.

Regards,

Orjan Nordle
Active Biotech
Lund
Sweden

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From: "Bachman, William" 
Subject: RE: [NMusers] Problems with Digital Visual Fortran vers 5.0 on Wi ndows NT 4.0
Date: Tue, 19 Mar 2002 15:45:29 -0500

Orjan,

The first thing I need to ask is "what command line arguments did you use
with setup.bat"?  This can be determined by looking at the contents of
setup.txt (found in c:\nmv directory if you used the default parameters).
If you used "df" you are ok.  If you used "fl32" or just typed "setup",  you
need to repeat the installation using "df", e.g.:
setup a c nmv df y link

You should be using level "D" if you are using Digital 5.0.  This can be
determined by typing "df" at a DOS command prompt and noting the version and
level reported, e.g. 5.0D.  Since this is an outdated version of the
compiler, the patch may not be available on the internet anymore.  Mail me
off the list if you need the file.  Updating to 5.0D should be sufficient.

As far as "The software is not as good as the old one.", if you are refering
to Windows 95, you will find that NT is actually far superior to 95, 98 or
ME once you get used to it.

nmconsult@globomaxnm.com
GloboMax LLC
7250 Parkway Drive, Suite 430
Hanover, MD 21076
Voice: (410) 782-2205
FAX: (410) 712-0737


*******

Subject: Re: [NMusers] Problems with Digital Visual Fortran vers 5.0 on Windows NT 4.0
Date: Wed, 20 Mar 2002 09:24:25 +1200
From: Nick Holford 

I would encourage anyone using earlier versions of the df compiler to upgrade (currently Compaq Visual
Fortran 6.6). The 6.6 compiler can get quite different NONMEM results from 6.0A which I am pretty confident
is due to improved numerical precision.

Same thing goes for Windoze. Win2000 is very stable and works well for running NONMEM (especially if you
can get hold of a dual CPU Intel box).



Nick

-- 
Nick Holford, Divn Pharmacology & Clinical Pharmacology
University of Auckland, 85 Park Rd, Private Bag 92019, Auckland, New Zealand
email:n.holford@auckland.ac.nz tel:+64(9)373-7599x6730 fax:373-7556
http://www.health.auckland.ac.nz/pharmacology/staff/nholford/

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