From david-bourne@uokhsc.edu Fri Mar 31 09:52:58 1995
Subject: Re: NONMEM on the PowerMac

Hello again

Absoft has come up with another version of their FORTRAN compiler for the Macintosh. This is V 4.1. I have recompiled the NONMEM files and put together another version of the help folder for other Macintosh/NONMEM users. Again the results are good (I think). I was able to optimize some files I couldn't before and not optimize one or two that optimized with v4.0 of the compiler. Oh well. The test runs are a little faster. I used the sample runs presented in:

NONMEM User's Guide Part III (Nov 92) Page 3. Using the NONMEM20-25 files.

------------------------------------------------------
        Time (sec)   File Size for          Memory        
                        NONMEM      Allocation set by    
                                      compiler/linker   
------------------------------------------------------
PRED        13           576K              1217K        
ADVAN2      20           576K              1217K        
ADVAN7      143          585K              1217K        
ADVAN6      216          585K       1217K   :-)         
------------------------------------------------------

as benchmarks. The timings etc. are shown above for a PowerMac6100/60AV. Times are about half the 1992 benchmark values. I've put together a few files including the make files for the Absoft compiler for the PowerMac v4.1. These are available at:

topic022b.sit

David Bourne, Ph.D.
OU HSC College of Pharmacy
Oklahoma City, OK 73117
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