From: josep-maria.cendros@beaufour-ipsen.com


Subject: [NMusers] Simulation step
Date: Mon, 22 Oct 2001 19:53:52 +0200

Dear all,

When I perform a simulation analysis using subproblem option ( $SIMULATION
(1879229) SUBPROBLEMS=100 ),NONMEM performs the first simulation
(SUBPROBLEM=1) without any problem. But when NONMEM tries to execute the
second simulation (SUBPROBLEM=2) the program stops and the following
message is printed:

**************************************************************************

PROBLEM NO.: 1 SUBPROBLEM NO.: 2

SIMULATION STEP PERFORMED
SOURCE 1:
SEED1: 1694998235 SEED2: 0

MONITORING OF SEARCH:

0SUBROUTINE GETETA NOT INITIALIZED

****************************************************************************

Does anybody know how to resolve this problem?

Thanks in advance.

Josep Maria Cendrós

*****

From: Joern.Loetsch@t-online.de (Joern Loetsch)
Subject: Re: [NMusers] Simulation step
Date: Mon, 22 Oct 2001 21:09:57 +0200

This is a known bug in NONMEM V. Go to
http://www.cognigencorp.com/nonmem/nm/99jul291998.html

anmd do what is advises
Regards

Joern
_______________________________________________________
Jorn Lotsch, MD
pharmazentrum frankfurt, Department of Clinical Pharmacology
Johann Wolfgang Geothe-University Hospital
Theodor-Stern-Kai 7
D-60590 Frankfurt
Germany
Phone: +49-69-6301-4589
Fax: +49-69-6301-7636