March 25, 2009

Kerfuffle! Published in Journal of Clinical Pharmacology

Kerfuffle!, a paper written by Cognigen scientists Ted Grasela, Beth Ludwig, and Jill Fiedler-Kelly, was published in the April 1, 2009, issue of the Journal of Clinical Pharmacology as part of the Innovations and Viewpoints section of the journal.

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Kerfuffle: to become disheveled. A kerfuffle is the polite term for a cascading series of errors that can be initiated by a seemingly innocuous event that then leads to other errors that gain in severity and impact. This article describes some of the common kerfuffles that arise in modeling and simulation efforts. The process of eradicating or minimizing the impact of these pharmacometric kerfuffles begins with the recognition that the errors that contribute to the kerfuffle can and should be addressed systematically. They are not just an unpleasant aspect of the job that pharmacometricians must learn to live with in the conscientious execution of their work. ©2009 the American College of Clinical Pharmacology

Grasela TH, Ludwig E, Fiedler-Kelly J. Kerfuffle! J Clin Pharmacol. 2009;49:386-388.


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Kerfuffle! Published in Journal of Clinical Pharmacology

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