NONMEM Users Network Archive

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From: Emmanuel Chigutsa <>
Date: Thu, 31 Dec 2015 16:31:44 +0000 (UTC)

Hi Thorsten,
You can change the default limits for various things using the $SIZES optio=
n. To change the limit of columns, add the following in the beginning of yo=
ur control stream (even before $PROBLEM)$SIZES PD=-100
This tells NONMEM that your dataset has 100 columns or less (change the val=
ue of PD as you see fit). Note that the minus sign is interpreted by NONMEM=
 that your dataset has up to 100 columns. Without the minus sign, NONMEM wi=
ll interpret your dataset to have exactly the number of columns you have sp=
Good luck.

      From: Zhu Xiao <>
 To: Thorsten Lehr <>; nmusers_at_globomaxnm.c=
 Sent: Thursday, December 31, 2015 8:51 AM

Dear Thorsten,
As far as I know, NONMEM allows no more than 50 data items; with NONME=
M versions 6 and earlier, only up to 20 data items were allowed. But y=
ou can still use "=DROP" to circumvent this limitation. You can drop the =
variables those are not used in the current model. Any subsetting requ=
ested via the IGNORE or ACCEPT is performed prior to dropping variable=
s. Therefore, those dropped variables could be used to specify data su=
bsets to NM-TRAN.
Happy holidays!

Reference:Joel S. Owen, Jill Fiedler-Kelly-Introduction to Population Pharm=
acokinetic Pharmacodynamic Analysis with Nonlinear Mixed Effects Models (20=
14) p35

At 2015-12-31 18:25:38, "Thorsten Lehr" <> =
wrote:>Dear nmusers,>>I'm using NONMEM 7.3 for a simple PK modeling analysi=
s. My dataset >contains 75 patients and about 2600 observations.>In my data=
set I have 65 data items. If I include more than 49 data items >in the $INP=
UT statement, I receive the following error message: "$INPUT: >NO. OF DATA =
ITEMS EXCEEDS PD.">>According to the NONMEM Users Guide there should be no =
limitation with >the number of data items in NM 7.2 and higher. Does anyone=
 has an idea >what is ongoing? Is there a way to include >49 data items?>>M=
any thanks and Happy New Year,>Thorsten>>-- >Thorsten Lehr, PhD>Junior Prof=
essor of Clinical Pharmacy>Saarland University>Campus C2 2>66123 Saarbr=
cken>Germany>>Office: +49/681/302-70255>Mobile: +49/151/22739489>thorste=>>



Received on Thu Dec 31 2015 - 11:31:44 EST

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