NONMEM Users Network Archive

Hosted by Cognigen

[NMusers] M&S Summer Internship at Allergan

From: Luu_Ken <Ken.Luu_at_allergan.com>
Date: Thu, 24 May 2018 23:15:08 +0000

The Pharmacometrics/Modelling and Simulation discipline at Allergan is seek=
ing a summer intern for 2018. The incumbent will be working under the direc=
tion of an M&S scientist to develop an ocular PBPK model to support researc=
h and translational science. The incumbent will be using a large database o=
f ocular tissue and serum PK data across many different investigational dru=
gs along with their physicochemical properties to establish and validate a =
mechanistic model with predictive capabilities with the intent to support f=
uture study designs and reduce animal use in alignment with our corporate 3=
R objectives.

Experience in the following areas is a plus: PBPK, nonlinear-mixed effects =
modelling with working knowledge NONMEM, WinNonlin, SAS and/or R programmin=
g.

Key responsibilities:

  * Develop and validate a predictive PBPK model
  * Mining Allergan internal, and if necessary, literature ocular PK data
  * Organize and program datasets to make them amendable for modelling
  * Perform data visualization
  * Create a centralized repository folder to store the data and model
  * Present data to group and symposium at the end of the program

The incumbent may attend project team and group meetings to gain industry/p=
roject-support experience

Qualifications
* B.S. or equivalent degree is required
* The ideal candidate is preferred to be enrolled in a doctoral or ma=
ster's program in one of the following disciplines: pharmacokinetics, pharm=
acometrics, pharmaceutical sciences, biostatistics, data programming or mat=
hematics.
* Must be enrolled as a full-time student at an accredited universit=
y and in good academic standing.
* Must have valid U.S. work authorization without the need for spons=
orship by the company.
* Must be able to work full-time for 10 weeks for the duration of th=
e internship.
* No relocation, transportation, or housing assistance will be provi=
ded

Ability to travel up to [0]% of time.

Note: While this job description is intended to be an accurate reflection =
of the job requirements, management reserves the right to modify, add or re=
move duties from a particular job and to assign other duties as necessary a=
nd at any time.

Email CV directly to: Ken.Luu_at_Allergan.com

Kenneth T. Luu, PhD
Director of Pharmacometrics, Allergan plc
2525 Dupont Dr. Irvine, CA 92610 Tel. 714-246-2803

This e-mail, including any attachments, is meant only for the intended reci=
pient of the transmission, and may be a confidential or privileged communic=
ation. If you received this e-mail in error, any review, use, dissemination=
, distribution, or copying of this e-mail is strictly prohibited. Please no=
tify us immediately of the error by return e-mail and please delete this me=
ssage from your system. Thank you in advance for your cooperation.


Received on Thu May 24 2018 - 19:15:08 EDT

The NONMEM Users Network is maintained by ICON plc. Requests to subscribe to the network should be sent to: nmusers-request@iconplc.com. Once subscribed, you may contribute to the discussion by emailing: nmusers@globomaxnm.com.