From: "Bachman, William (MYD)"
Subject: [NMusers] NONMEM Tips #22 - June 20, 2005 - Upgrading to Intel 9.0Fortran for Windows 
Date: Mon, June 20, 2005 3:46 pm 

The most difficult part of upgrading your NONMEM and/or Pdx-Pop
Installations to use Intel 9.0 Fortran for Windows is the installation of
Intel's new compiler.  For some reason, the instructions they provide are
never quite clear (IMO) and the licensing issue compounds the problems.
Once the new compiler is installed however, installation and running of
NONMEM and PDx-Pop are trivial.

The initial problem I encountered with the Intel installation was using the
option to use a serial number.  I kept getting "you have used an invalid
serial number" no matter how many times I contacted Intel support and
verified the number.  Once I switched to the option to use a license file
(supplied as an email attachment by Intel), installation proceeded without
further issues.

The other issue you may encounter is if you have previous versions of Intel
Fortran installed on your system.  The environmental variables may still
have settings that point to previous versions of the compiler so that if you
run the compiler command ("ifort") from a DOS window, it may tell you that
you are running version 8.0 instead of 9.0.  To circumvent this issue,
manually edit your system environment variables.  (Remove paths to version
8.0 from the PATH, LIB & INCLUDE variables and replace, as necessary, with
the correct paths for version 9.0.)  The ifortvars.bat (found in the
"C:\Program Files\Intel\Compiler\Fortran\9.0\IA32\Bin" directory (for my
installation) will provide the information you need for the variables for
version 9.0.

Once you have modified your environment, test that you are getting version
9.0 by running "ifort" from a DOS window.  The response should look
something like:

Intel(R) Fortran Compiler for 32-bit applications, Version 9.0    Build
20050430Z Package ID: W_FC_P_9.0.018
Copyright (C) 1985-2005 Intel Corporation.  All rights reserved.

ifort: Command line error: no files specified; for help type "ifort -help"

I then ran the following tests:
(1) setup.bat (version 4.0 )to test installing NONMEM using the new compiler
(no problems were encountered with the installation of NONMEM):

 setup a c nmi9 ifort y link

(Similarly, no problems were encountered with the CDsetup.bat found on the
CD-ROM distribution of NONMEM.  "D:> cdsetup d c nmi9cd ifort y link")

(2) running the control5 test problem:

C:\nmi9\run> nmfe5 control5 report5.txt

or (3) running PDx-Pop with the new compiler (the nonmemdir entry was
changed in the PDx-Pop.ini to reflect the new directory that I used).

Tests were done on a system running Microsoft Windows 2000 Professional.  No
compatibility problems with Windows XP are anticipated.

William J. Bachman, Ph.D.
Manager, Pharmacometrics Research and Development
The Strategic Pharmaceutical Development Division of ICON plc
7250 Parkway Drive, Suite 430
Hanover, MD 21076 

From: "Leonid Gibiansky"
Subject:  Re: [NMusers] NONMEM Tips #22 - June 20, 2005 - Upgrading to Intel9.0 Fortran for Windows 
Date: Sat, June 25, 2005 6:38 am

Do you have some standard tests / benchmarks to compare performance (more exactly,
speed) of NONMEM 
on different compilers? Vladimir indicated that Intel is much faster than Digital in
some of the 
examples. I wonder whether you have any way to check, compare and recommend what is
the fastest way 
to run NONMEM. Specifically, comparison between g77, Digital and Intel would be very
helpful. I 
guess, optimization options can play a role, any recommendation would be
appreciated. From what I 
have seen/heard, g77 is the most stable of those but it would be very interesting to
compare the 
speed as well. Any advices on OS (assuming that they are used on the same CPU):
Windows 2000, XP vs