From: "Piotrovskij, Vladimir [JanBe]" <>
Subject: Steady-state equation
Date: Fri, 2 Jul 1999 08:20:18 +0200

Dear NONMEM users,
I apologise for this non-NONMEM question. For the one-compartment model with equal absorption and elimination rate constants the single-dose profile is given by Cp=FD/V*k*t*exp(-k*t). Is anybody aware of corresponding analytical multiple-dose and steady-state equations? Any references would be appreciated. Please send replies (if any)directly to me to minimise using nmusers' list for the non-relevant question.

Thanks in advance,
Vladimir Piotrovsky, Ph.D.
Janssen Research Foundation
Clinical Pharmacokinetics
B-2340 Beerse